home.md

-## What is LocScale?
+## About
     
     
 LocScale is a reference-based local amplitude scaling tool that used prior model information to improve contrast of cryo-EM density maps.  
@@ -9,17 +9,20 @@ To reliably reflect the required level of local sharpening and local resolution
      
 <img src="https://git.embl.de/jakobi/LocScale/raw/master/doc/img/EM_cyle_DM_1.jpg" width="400">
 
-<br>
-  
-
-  
-#### [__LocRes__](LocRes)   - local resolution estimation based on windowed FSC calculation
 
 #### [__LocScale__](LocScale) - local sharpening based on reference-based amplitude scaling
-<br>
-#### The program is available here for [Download ](https://git.embl.de/jakobi/LocScale/tree/master/download).  
+
+#### The program is available [here] (https://git.embl.de/jakobi/LocScale/tree/master/download) for download.  
 <br>
 
+[//]: # (#### [__LocRes__](LocRes)   - local resolution estimation based on windowed FSC calculation)
 [//]: # ([__LocFSC__](LocFSC)   - local model validation based on FSC<sub>ref</sub> calculations)  
 
+## Dependencies  
+  
+LocScale is written in [Python](https://www.python.org/) and in part based on libraries from [SPARX](http://sparx-em.org) and [CCTBX](https://github.com/cctbx/cctbx_project).  
+LocScale is dependent on [NumPy and SciPy](http://www.numpy.org/) and [mpi4py](http://pythonhosted.org/mpi4py/).
+
+
+LocScale   
 [[1]](https://doi.org/10.1101/121913) Jakobi et al. bioRxiv 121913 (2017)  
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